E X T O X N E T
Extension Toxicology Network
A Pesticide Information Project of Cooperative Extension Offices of
Cornell University, Michigan State University, Oregon State University, and
University of California at Davis. Major support and funding was provided
by the USDA/Extension Service/National Agricultural Pesticide Impact
Assessment Program.
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Pesticide
Information
Profile
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Fluazifop-p-butyl
Publication Date: 9/93
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TRADE OR OTHER NAMES
Trade names for commercial products containing this herbicide
include Tornado, Fusilade 2000, Fusilade Five, and Fusilade Super. The
compound is compatible with a wide variety of other herbicides. The
compound is also found in formulations with the herbicide fomesafen.
INTRODUCTION
Fluazifop-p-butyl is a selective phenoxy herbicide used for
postemergence control of annual and perennial grass weeds. It is used
on soybeans and other broad-leaved crops such as carrots, spinach,
potatoes, and ornamentals.
Fluazifop-p-butyl is a general use pesticide.
NOTE: This herbicide is a different compound than either fluazifop or
fluazifop butyl. Both the chemical structures and the toxicities of
these compounds are different. Fluazifop-p-butyl formulations can
contain some fluazifop-butyl.
TOXICOLOGICAL EFFECTS
ACUTE TOXICITY
Fluazifop-p-butyl is a slightly toxic compound which carries the
signal word CAUTION on its label. A single dose of the formulated
compound (Fusilade 2000) can cause severe stomach and intestine
disturbance. Ingestion of large quantities may cause problems in the
central nervous system such as drowsiness, dizziness, loss of
coordination and fatigue. Breathing small amounts of the product may
cause vomiting and severe lung congestion. This may ultimately lead to
labored breathing, coma and death (1).
The acute oral LD50 of fluazifop-p-butyl is 3,680 for male rats and
2,451 for female rats. The dermal LD50 for the compound is greater than
2,450 in rabbits. This value indicates that the compound has a low to
moderate toxicity when in contact with the skin. It is only a mild skin
and eye irritant and causes no skin sensitization (2).
CHRONIC TOXICITY
Rats fed small amounts of fluazifop-p-butyl for three months
developed no compound induced effects at doses at or below 10 mg/kg.
Reproductive Effects
No information is currently available.
Teratogenic Effects
No information is currently available.
Carcinogenic Effects
No information is currently available.
Mutagenic Effects
No information is currently available.
Organ Toxicity
No information is currently available.
Fate in Humans and Animals
No information is currently available.
ECOLOGICAL EFFECTS
Fluazifop-p-butyl is practically non-toxic to mallard ducks. Its
acute oral LD50 in mallards is greater than 3,528 mg/kg. Values for
other species are not currently available, thus its overall toxicity to
birds, invertebrates, and mammals cannot be adequately assessed. The
compound does, however, have a very low toxicity to bees. Oral and
contact LD50s for bees are greater than 0.20 mg/bee (2).
ENVIRONMENTAL FATE
Fluazifop-p-butyl breaks down rapidly in moist soils. Its half-
life in moist conditions is generally less than a week (2). The major
degradation product of fluazifop-p-butyl will also break down fairly
rapidly. Its half-life is around three weeks.
Fluazifop-p-butyl is actively taken up by plants and translocated
throughout the plant. The compound accumulates in the actively growing
regions of the plant (shoots, root rhizomes, stolons of grass) where it
interferes with the plant cell's ability to produce energy. In plants,
fluazifop-p-butyl is rapidly broken down in the presence of water to
fluazifop-p.
Exposure Guidelines:
Physical Properties:
| CAS #: | 69806-50-4 |
| Chemical name: | (R)2-[4[445[-(trifluoro-methyl)-2-pyridinyl]oxy]-phenoxy] propanoate |
| Chemical class/use: | Phenoxy, trifluoromethyl, pyridine herbicide |
| Solubility in water: | 1 mg/l |
| Solubility in other solvents: | soluble in most organic solvents |
| Melting point: | 5 degrees C |
| Vapor Pressure: | 0.054 mPa at 20 degrees C |
| Stability: | Compound is stable to UV light; decomposes at 210 degrees C |
BASIC MANUFACTURER
Zeneca Ag Products
Wilmington, Delaware 19897
Telephone 800-323-8633
Review by Basic Manufacturer:
Comments solicited: December, 1992
Comments received:
REFERENCES
Material Safety Data Sheet. ICI Americas Inc. Fusilade 2000.
The Agrochemicals Handbook. 1991. The Royal Society of Chemistry.
Cambridge, England.
Disclaimer: Please read
the pesticide label prior to use. The information contained at this web
site is not a substitute for a pesticide label. Trade names used herein
are for convenience only; no endorsement of products is intended, nor is
criticism of unnamed products implied. Most of this information is historical
in nature and may no longer be applicable.
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