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Pesticide
Information
Profile
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Hydramethylnon
Publication Date: 9/93
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TRADE OR OTHER NAMES
Some trade names include ACJ217,300, Amdro and Maxforce.
REGULATORY STATUS
Products containing hydramethylnon must bear the signal word "Caution"
(1).
INTRODUCTION
Hydramethylnon is an insecticide used in baits to control fire ants,
leafcutter ants and cockroaches (1).
TOXICOLOGICAL EFFECTS
The toxicological properties of hydramethylnon have not been fully
investigated (2).
ACUTE TOXICITY
Hydramethylnon is moderately toxic by ingestion and slightly toxic by
dermal adsorption (2). It is not irritating to skin or eyes (2).
The oral LD50 for technical hydramethylnon in male rats is 1,131 mg/kg,
and 1,300 mg/kg in female rats. The dermal LD50 on rabbits is > 5,000 mg/kg
(1).
CHRONIC TOXICITY
Chronic NOEL levels of 50 mg/kg for rats and 3 mg/kg for dogs have been
reported (2).
Reproductive Effects
No information was found.
Teratogenic Effects
Hydramethylnon is non-teratogenic and non-embryotoxic in rats and rabbits
(5).
Mutagenic Effects
Hydramethylnon is non-mutagenic (5).
Carcinogenic Effects
No information was found.
Organ Toxicity
No information was found.
Fate in Humans and Animals
In rats, following oral administration, hydramethylnon was rapidly
eliminated in the feces and urine. No residues were detectable in the milk or
tissues of goats (0.2 mg/kg in the daily diet for 8 days). No residues were
found in the milk or tissues of cows (0.05 mg/kg for 21 consecutive days).
ECOLOGICAL EFFECTS
Effects on Birds
The oral LD50 for hydramethylnon in mallard ducks is > 2,510 mg/kg, and
in bobwhite quail is 1,828 mg/kg (1).
Effects on Aquatic Organisms
Hydramethylnon is toxic to fish (4). The 96-hour LC50 for
hydramethylnon in rainbow trout is 0.16 mg/l, 0.10 mg/l in channel catfish,
and 1.70 mg/l in bluegill sunfish (1).
Hydramethylnon accumulated in bluegill sunfish at 1,300 times its
concentration in surrounding waters (4).
Effects on Other Animals (Nontarget species)
Hydramethylnon is non-toxic to honey bees (5).
ENVIRONMENTAL FATE
Breakdown of Chemical in Soil and Groundwater
Because hydramethylnon is only slightly soluble in water and has a very
strong tendency to adsorb to soil particles, it is not mobile in soil and is
unlikely to contaminate groundwater (3). When radio-labeled Amdro, a granular
bait formulation, was applied to an aged soil column under laboratory
conditions, 72% of the applied radioactivity remained in the treated soil
after 45 days. Less than 0.2% of the radioactivity was recovered in
leachate. This evidence supports the conclusion that neither Amdro nor
its metabolites leach (4).
A soil half-life of 10 days has been reported (3). EPA reports a soil
half-life of 18 hours, with breakdown probably due to decomposition by light
and the rapid foraging of ants (4).
Breakdown of Chemical in Surface Water
No information was found.
Breakdown of Chemical in Vegetation
Over a 90-day rotation interval, hydramethylnon did not accumulate in
crop plants planted after harvest of a treated crop (4). In another study,
residues in grass 4 months after treatment were <0.01 ppm. Negligible
residues were found in radishes, braley, and French beans planted 3 months
after treatment of the soil (5).
PHYSICAL PROPERTIES AND GUIDELINES
Hydramethylnon is a yellow to orange solid. It is stable under normal
temperatures and pressures, but may pose a slight fire hazard if exposed to
heat or flame. It may burn, but does not ignite readily. It poses a fire and
explosion hazard in the presence of strong oxidizers. Thermal decomposition
of hydramethylnon may release highly toxic fumes of fluorides and oxides of
nitrogen and carbon (2).
Exposure Guidelines:
No occupational exposure limits have been established for
hydramethylnon by OSHA, NIOSH or ACGIH (2).
Physical Properties:
| CAS #: | 67485-29-4 |
| Chemical name: | Tetrahydro-5,5-dimethyl-2(1H)-pyrimidinone {3-{4-(trifluoromethyl) phenyl}-1-{2-{4-trifluoromethyl) phenyl} ethenyl}-2-propenyl-idene} hydrazone |
| Chemical Class/Use: | pyrimidine hydrazone insecticide |
| H20 solubility: | 5-7 ppb at 25 degrees C (1); 0.006 ug/ml (3) |
| Solubility in other solvents: | soluble in acetone, chlorobenzene, hot ethyl acetate, and methylene chloride; slightly soluble in methanol, ethanol, and isopropanol (1). |
| Melting point: | 365- 374 degrees F (185-190 degrees C) (2) |
| Vapor pressure: | 2 x 10-8 mm Hg (3); negligible (2) |
| Koc: | 1,000,000 (3) |
BASIC MANUFACTURER
American Cyanamid Co.
One Cyanamid Plaza
Wayne, NJ 07470
Emergency: 201-831-2000
Review by Basic Manufacturer:
Comments solicited: April, 1993
Comments received:
REFERENCES
Meister, R.T. (ed.). 1992. Farm Chemicals Handbook '92. Meister
Publishing Company, Willoughby, OH.
Occupational Health Services, Inc. 1992 (Nov. 17). MSDS for
Hydramethylnon. OHS Inc., Secaucus, NJ.
U. S. Department of Agriculture, Soil Conservation Service. 1990
(Nov.). SCS/ARS/CES Pesticide Properties Database: Version 2.0
(Summary). USDA - Soil Conservation Service, Syracuse, NY.
US Environmental Protection Agency. March 19, 1992. Pesticide
Environmental Fate One Line Summary: Hydramethylnon. Environmental Fate
and Effects Division, US EPA, Washington, DC.
The Agrochemical Handbook. 1991. The Royal Society of Chemistry.
Cambridge, England.
Disclaimer: Please read
the pesticide label prior to use. The information contained at this web
site is not a substitute for a pesticide label. Trade names used herein
are for convenience only; no endorsement of products is intended, nor is
criticism of unnamed products implied. Most of this information is historical
in nature and may no longer be applicable.
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