PMEP Home Page --> Pesticide Active Ingredient Information --> Fungicides and Nematicides --> Acetic acid to Etridiazole --> ampelomyces quisqualis (AQ10) --> ampelomyces quisqualis (AQ10) NYSDEC Registration of New Active Ingredient 1/96

ampelomyces quisqualis (AQ10) NYSDEC Registration of New Active Ingredient 1/96

JAN 12 l996
Ms. Marion A. Burgwin
Regulatory Specialist
P.O. Box 3023
Langhorne, PA 19047-3023

Dear Ms. Burgwin:

Re:  Registration of the New Active Ingredient Ampelomyces quisqualis
     Isolate M10; Contained in the Pesticide Product AQ10 Biofungicide
     (EPA Reg. No. 55638-16)

Ecogen Inc. applied for New York State registration for AQ10 
Biofungicide (EPA Reg. No. 55638-16) which contains the new active 
ingredient Ampelomyces quisqualis Isolate M10.

AQ10 Biofungicide is a fungus that parasitizes powdery mildew.  
Following rehydration and application, AQ10 spores germinate into the 
powdery mildew mycelia and parasitize it.  AQ10 Biofungicide is for use 
to control powdery mildew on the following field and greenhouse crops: 
apples, cucurbits, grapes, ornamentals, strawberries and tomatoes.  The 
application rate is 1 oz./acre, which is equal to 0.036 lb. active 
ingredient/acre, or 1.4 x 1011 viable spores/acre.  The estimated 
maximum number of applications is 12 per season or 0.43 lb. active
ingredient/acre per season.

The New York State Department of Environmental Conservation (the 
Department) has completed the review of the information supplied to date 
in support of the pesticide product registration application for AQ10 
Biofungicide, which contains the new active ingredient Ampelomyces 
quisqualis Isolate M10.

Ampelomyces quisqualis Isolate M10 is a naturally occurring biological 
pesticide and the United States Environmental Protection Agency (EPA) 
required only limited toxicological and non-target organism data.  The 
EPA waived all other data requirements for this product, including 
chronic mammal and avian, freshwater fish, marine/estuarine, aquatic 
plant, and environmental fate studies, due to its nontoxic nature and 
target specificity.  The EPA did not require data on crop residues and 
determined that establishment of a tolerance for food crops is not 
necessary to protect the public health from AQ10 Biofungicide use.

,
Ampelomyces quisqualis Isolate M10 does not appear to be very toxic or 
pathogenic in laboratory animals.  There have been no reported cases of 
adverse reactions associated with the production or use of AQ10 
Biofungicide.  The uses specified on the AQ10 Biofungicide product label 
should neitner significantly increase exposure of the general population 
to Ampelomyces quisqualis Isolate M10 nor pose risks to workers adhering 
to the personal protection equipment requirements and recommendations.  

Therefore, the Department hereby accepts AQ10 Biofungicide (EPA Reg. No. 
55638-16) for registration.

Enclosed are your New York State stamped "ACCEPTED" label and a copy of 
the Certificate of Registration.

Please contact Ms. Maureen Serafini, of my staff, at (518) 457-7446, if 
you have any questions.

Sincerely,



Norman H. Nosenchuck, P.E.
Director
Division of Solid & Hazardous Materials

Enclosures
cc: w/enc.:  N. Kim - NYSDOH
             A. Grey - NYSDOH
             N. Rudgers/R. Mungari - NYS Dept. of Ag & Markets
             D. Rutz/W. Smith - Cornell University