carboxin (Vitavax) Chemical Profile 1/85
CHEMICAL NAME: 5,6-dihydro-2-methyl-1,4-oxathiin-3-carboxamide (56)
TRADE NAME(S): Vitavax (48)
FORMULATION(S): 75% wettable powder, 17% flowable, in combination
with captan and thiram (48).
TYPE: Organic fungicide
BASIC PRODUCER(S): Uniroyal Chemical Co.
STATUS: General use
PRINCIPAL USES: Systemic seed protectant for wheat, oats, corn and
barley seed against smuts, bunts and other diseases (48).
Used against Rhizoctonia spp. of vegetables (26).
To be developed.
II. PHYSICAL PROPERTIES
MOLECULAR FORMULA: C12 H13 NO2 S (26)
MOLECULAR WEIGHT: 235.3 (26)
PHYSICAL STATE: Colorless solid (pure compound) (26)
MELTING POINT: 91.5-92.5 C; a dimorphic form has m.p. 98-100 C
(pure compound) (26).
SOLUBILITY: 170 mg/l water at 25 C (pure compound) (26)
III. HEALTH HAZARD INFORMATION
OSHA STANDARD: NA
NIOSH RECOMMENDED LIMIT: NA
ACGIH RECOMMENDED LIMIT: NA
A. ACUTE TOXICITY
DERMAL: LD50 = >8000 mg/kg (rabbit) (56)
ORAL: LD50 = 3820 mg/kg (rat) (56)
B. SUBACUTE AND CHRONIC TOXICITY:
In 2-year feeding trials albino rats receiving 600 mg/kg diet
suffered no detectable symptom (26).
IV. ENVIRONMENTAL CONSIDERATIONS
Hazardous to fish. Relatively nonhazardous to honey bees.
Nonphytotoxic when used as directed. Does not persist in the soil (48).
V. EMERGENCY AND FIRST AID PROCEDURES
The chemical information provided below has been condensed
from original source documents, primarily from "Recognition and
Management of Pesticide Poisonings", 3rd ed. by Donald P. Morgan,
which have been footnoted. This information has been provided in
this form for your convenience and general guidance only. In
specific cases, further consultation and reference may be required
and is recommended. This information is not intended as a sub-
stitute for a more exhaustive review of the literature nor for the
judgement of a physician or other trained professional.
If poisoning is suspected, do not wait for symptoms to develop.
Contact a physician, the nearest hospital, or the nearest Poison
SKIN CONTACT: Flush with plenty of water. Wash skin with soap
and water (21c).
INGESTION: Induce vomiting and see a physician (41b).
INHALATION: See a physician if an abnormal reaction occurs
EYE CONTACT: Flush with plenty of water (21c).
VI. FIRE AND EXPLOSION INFORMATION
To be developed.
Compatible with other pesticides used as seed treatments (48).
VIII. PROTECTIVE MEASURES
STORAGE AND HANDLING: Do not contaminate food or feedstuffs. Keep out
of reach of children. Avoid inhaling dust or spray mist. Do not get
in eyes or on skin. Do not graze or feed livestock on treated areas
for ten weeks after planting. Do not spill treated grain or otherwise
expose to wild birds. Do not store treated seed longer than one year
(21c). Store in a cool dry place (56).
PROTECTIVE EQUIPMENT: Wear a mask suitable for protection against
Vitavax dust or spray vapors when applying this chemical to seed (21c).
IX. PROCEDURES FOR SPILLS AND LEAKS
IN CASE OF EMERGENCY, CALL, DAY OR NIGHT
PESTICIDE TEAM SAFETY NETWORK/CHEMTREC
X. LITERATURE CITED
21c. Canada Department of Agriculture, Production and Marketing Branch,
Plant Products Division. 1970. Memorandum (re: Vitavax).
Ottawa, Ontario, Canada.
26. The Pesticide Manual: A World Compendium, 6th ed. 1979. C. R.
Worthing, ed. The British Crop Protection Council, Croydon,
England. 655 pp.
41b. Uniroyal Chemical, Division of Uniroyal, Inc. 1977. Specimen
label: Vitavax fungicide. Naugatuck, CT.
48. Harding, W.C. 1979-80. Pesticide profiles, part two: fungicides
and nematicides. Univ. Maryland, Coop. Ext. Service Bull.
283, 22 pp.
56. Farm Chemicals Handbook, 70th ed. 1984. R. T. Meister, G. L.
Berg, C. Sine, S. Meister, and J. Poplyk, eds. Meister
Publishing Co., Willoughby, OH.