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Copper Hydroxide - Chemical Profile 1/85

                                  copper hydroxide

      CHEMICAL name:      Cupric hydroxide (6)

      TRADE name(S):      Kocide (48)

      FORMULATION(S):     Wettable powder, dust, 30% flowable; also combined
                          with sulfur and copper oxychloride (48).
                             Kocide 101 Wettable Powder containing 77% cupric
                          hydroxide (copper equivalent 50%).
                             Kocide 606 contains 6 pounds Kocide 101/gallon;
                          37.5% copper hydroxide (copper equivalent 24.4%).
                          Broad spectrum fungicide registered for use on
                          the same crops as Kocide 101.
                             Kocide SD Seed Dressing is a flowable formulation

                          containing 30% cupric hydroxide (copper equivalent
                          19.5%).  Cleared for use on rice seed and wheat
                          and barley seed (56).

      TYPE:               Inorganic fungicide

      BASIC PRODUCER(S):  Kocide Chemical Corp.
                          12701 Almeda Rd.
                          P.O. Box 45539
                          Houston, TX 77045

      STATUS:             General use

      PRINCIPAL USES:  Used as broad spectrum foliar fungicide on fruits,
      vegetables and ornamentals (48).  Kocide 101 has been cleared for use
      on alfalfa, almonds, apricots, beans, blackberries, broccoli, Brussels
      sprouts, cabbage and cauliflower, cantaloupes, honeydews, muskmelons,
      carrots, celery, cherry, cranberry, cucumbers, currants, gooseberry,
      grapes, filberts, peaches, nectarines, peanuts, pears, peas, peppers,
      potatoes, pumpkin, squash, strawberries, apples, eggplant, hops,
      lettuce, onion, sugar beets, sycamore, tomatoes, walnut, watermelon,
      wheat, and barley (56).

                                   I.  EFFICACY

           To be developed.

                             II.  PHYSICAL PROPERTIES

      MOLECULAR FORMULA:  CU (OH)2 (3)

      PHYSICAL STATE:     Blue powder (3)

      MELTING POINT:      Decomposes (3)

      SOLUBILITY:         Insoluble in water (3)

                          III.  HEALTH HAZARD INFORMATION

      OSHA STANDARD:  NA

      NIOSH RECOMMENDED LIMIT:  NA

      ACGIH RECOMMENDED LIMIT:  NA

      TOXICOLOGY

           A.  ACUTE TOXICITY

               ORAL:  LD50 = 1000 mg/kg (48)

           B.  SUBACUTE AND CHRONIC TOXICITY:

           To be developed.

                        IV.  ENVIRONMENTAL  CONSIDERATIONS

           Hazardous to fish.  Nonphytoxic when used as directed.  Russeting
      of pears occurs at high rates (48).

                      V.  EMERGENCY AND FIRST AID PROCEDURES

           The chemical information provided below has been condensed
      from original source documents, primarily from "Recognition and
      Management of Pesticide Poisonings", 3rd ed. by Donald P. Morgan,
      which have been footnoted.  This information has been provided in
      this form for your convenience and general guidance only.  In
      specific cases, further consultation and reference may be required
      and is recommended.  This information is not intended as a sub-
      stitute for a more exhaustive review of the literature nor for the
      judgement of a physician or other trained professional.

           If poisoning is suspected, do not wait for symptoms to develop.
      Contact a physician, the nearest hospital, or the nearest Poison
      Control Center.

      FREQUENT SYMPTOMS AND SIGNS OF POISONING

           All of these salts (including copper hydroxide) irritate the skin
      and eyes and damage mucous membranes.  When ingested, they are
      powerfully emetic:  the stomach usually empties promptly and
      automatically in fully conscious individuals.  When retained and
      absorbed, toxic injury affects the gastrointestinal lining,
      capillaries, brain, liver, kidney, and formed elements of the blood.
      Copper salts are hemolytic.

           Manifestations of poisoning include burning in the chest and
      abdomen, intense nausea, vomiting, diarrhea, headache, sweating and
      shock.  Later, the liver is enlarged.  Jaundice may reflect hemolysis
      or liver damage or both.  Anuria indicates kidney injury by copper
      and/or free hemoglobin.  Death may occur from convulsions, coma, or
      hepatorenal failure.  Elevated serum copper levels (maximum normal
      level is 125 ug per 100 ml) indicate severity of poisoning (25).

           SKIN CONTACT:  Wash contaminated skin (25).

           EYE CONTACT:   Flush eyes with copious amounts of water (25).

      NOTES TO PHYSICIAN:

           Wash contaminated skin and flush eyes with copious amounts of
      water.  If copper salts have been ingested, lavage the stomach with
      0.1% potassium ferrocyanide, then instill a suspension of egg white.
      Intravenous fluids accelerate excretion.  If signs of systemic
      poisoning develop, give dimercaptrol or penicillamine, 0.5 mg orally
      four times daily, if patient can retain oral medication.  Shock may
      require blood transfusions and pain may require morphine.  Exchange
      transfusions may be considered in severe poisonings.  Renal failure may
      require protracted hemodialysis (25).

                        VI.  FIRE AND EXPLOSION INFORMATION

           To be developed.

                                VII.  COMPATIBILITY

           Compatible with most other pesticides.  Some formulations should
      not be mixed with water.  Check label (48).

                            VIII.  PROTECTIVE MEASURES

           To be developed.

                       IX.  PROCEDURES FOR SPILLS AND LEAKS

                     IN CASE OF EMERGENCY, CALL, DAY OR NIGHT
                                  (800) 424-9300
                      PESTICIDE TEAM SAFETY NETWORK/CHEMTREC

                               X.  LITERATURE CITED

       3.  The Condensed Chemical Dictionary, 8th ed.  1971.  VanNostrand
               Reihnold Co., New York, NY.  971 pp.

       6.  Farm Chemicals Handbook, 66th ed.  1980.  G. L. Berg, C. Sine,
               S. Meister, and H. Shephard, eds.  Meister Publ. Co.,
               Willoughby, OH.

      25.  Morgan, D.P.  1982.  Recognition and management of
               pesticide poisonings, 3rd ed.  U. S. Environmental Protection
               Agency, Washington, DC.  120 pp.

      48.  Harding, W.C.  1979-80.  Pesticide profiles, part two:  fungicides
               and nematicides.  Univ. Maryland, Coop. Ext. Service Bull.
               283, 22 pp.

      56.  Farm Chemicals Handbook, 70th ed.  1984.  R. T. Meister, G. L.
               Berg, C. Sine, S. Meister, and J. Poplyk, eds.  Meister
               Publishing Co., Willoughby, OH.

      1/31/85