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dodine (Cyprex) Chemical Profile 2/85

                                       dodine

      CHEMICAL NAME:      n-Dodecylguanidine acetate (56)

      TRADE NAME(S):      Cyprex, Melprex (56)

      FORMULATION(S):     Wettable powder, 65% (56)

      TYPE:               Organic fungicide

      BASIC PRODUCER(S):  American Cyanamid Co.
                          Agricultural Div.
                          P.O. Box 400
                          Princeton, NJ 08540

      STATUS:  General use

      PRINCIPAL USES:  Foliar eradicant/protectant against various
      diseases on fruits and nuts.  Nonsystemic (48).
           For control of scab on apples and pears; leafspot on cherries;
      foliar diseases of strawberries; bacterial leafspot on peaches; leaf
      blight of sycamores and blackwalnuts (56).


                                   I.  EFFICACY

           Cyprex has consistently demonstrated outstanding control of apple
      scab.  Under moderate disease conditions, 1/3 lb. Cyprex 65-W per 100
      has given effective control of Brooks Spot and Fly Speck (on apples).
      Cyprex 65-W and Cyprex 3% and 4% dusts have given outstanding control
      of pear scab.  Cyprex 65-W has given outstanding control of leaf spot
      in all regions of North America where the disease is economically
      important (on cherries) (30d).


                             II.  PHYSICAL PROPERTIES

      MOLECULAR FORMULA:  C15 H33 N3 O2 (26)

      MOLECULAR WEIGHT:   287.4 (26)

      PHYSICAL STATE:     Colorless crystals (pure compound) (26)

      MELTING POINT:      136 C (pure compound) (26)

      SOLUBILITY:         Soluble in water (pure compound) (26)


                          III.  HEALTH HAZARD INFORMATION

      OSHA STANDARD:  NA

      NIOSH RECOMMENDED LIMIT:  NA

      ACGIH RECOMMENDED LIMIT:  NA

      TOXICOLOGY

           A.  ACUTE TOXICITY

               DERMAL:  LD50 = >1500 mg/kg (rabbit, by single 24-hour skin
                        contact) (56).

               ORAL:    LD50 = about 1000 mg/kg (male rat) (56).

               EYES:    Concentrated material causes eye irritation (30d).

           B.  SUBACUTE AND CHRONIC TOXICITY:

           In 2-year feeding trials rats receiving 800 mg/kg diet suffered a
      slight retardation of growth with no effect on reproduction or
      lactation (26).


                        IV.  ENVIRONMENTAL  CONSIDERATIONS

           Nonhazardous to bees.  Phytotoxic effects on some varieties of
      apples, peaches, plums and nuts (48).


                      V.  EMERGENCY AND FIRST AID PROCEDURES

           The chemical information provided below has been condensed
      from original source documents, primarily from "Recognition and
      Management of Pesticide Poisonings", 3rd ed. by Donald P.  Morgan,
      which have been footnoted.  This information has been provided in
      this form for your convenience and general guidance only.  In
      specific cases, further consultation and reference may be required
      and is recommended.  This information is not intended as a sub-
      stitute for a more exhaustive review of the literature nor for the
      judgement of a physician or other trained professional.

           If poisoning is suspected, do not wait for symptoms to develop.
      Contact a physician, the nearest hospital, or the nearest Poison
      Control Center.

           EYE CONTACT:   Flush with plenty of water for at least fifteen
      minutes and get medical attention (30d).


                        VI.  FIRE AND EXPLOSION INFORMATION

           To be developed.


                                VII.  COMPATIBILITY

           Incompatible with chlorobenzilate, lime, oils and oil emulsions.
      Hard water causes some incompatibility (48).


                            VIII.  PROTECTIVE MEASURES

      STORAGE AND HANDLING:  Do not get in eyes or on skin.  Do not breathe
      dust.  Keep container closed when not in use.  Transfer or mix product
      under conditions of adequate ventilation.  Do not contaminate food or
      feed products.  Store this product away from food or feed.  The
      biological activity of the product remains practically unvaried for 3
      years under environmental conditions, provided the product is stored in
      its unopened and undamaged original containers, in shaded and possibly
      well-aired places (56).

      PROTECTIVE CLOTHING:  Wear goggles or face shield when handling.  Wear
      rubber gloves when handling and wash thoroughly after work (56).


                       IX.  PROCEDURES FOR SPILLS AND LEAKS

                     IN CASE OF EMERGENCY, CALL, DAY OR NIGHT
                                  (800) 424-9300
                      PESTICIDE TEAM SAFETY NETWORK/CHEMTREC


                               X.  LITERATURE CITED

      26.  The Pesticide Manual:  A World Compendium, 6th ed.  1979.  C. R.
               Worthing, ed.  The British Crop Protection Council, Croydon,
               England.  655 pp.

      30d. American Cyanamid Company, Agricultural Division.  1966.  Technical
               information:  Cyprex fruit fungicide.  Princeton, NJ.

      48.  Harding, W.C.  1979-80.  Pesticide profiles, part two:  fungicides
               and nematicides.  Univ. Maryland, Coop. Ext. Service Bull.
               283, 22 pp.

      56.  Farm Chemicals Handbook, 70th ed.  1984.  R. T. Meister, G. L.
               Berg, C. Sine, S. Meister, and J. Poplyk, eds.  Meister
               Publishing Co., Willoughby, OH.

      2/5/85