dodine (Cyprex) Chemical Profile 2/85
CHEMICAL NAME: n-Dodecylguanidine acetate (56)
TRADE NAME(S): Cyprex, Melprex (56)
FORMULATION(S): Wettable powder, 65% (56)
TYPE: Organic fungicide
BASIC PRODUCER(S): American Cyanamid Co.
P.O. Box 400
Princeton, NJ 08540
STATUS: General use
PRINCIPAL USES: Foliar eradicant/protectant against various
diseases on fruits and nuts. Nonsystemic (48).
For control of scab on apples and pears; leafspot on cherries;
foliar diseases of strawberries; bacterial leafspot on peaches; leaf
blight of sycamores and blackwalnuts (56).
Cyprex has consistently demonstrated outstanding control of apple
scab. Under moderate disease conditions, 1/3 lb. Cyprex 65-W per 100
has given effective control of Brooks Spot and Fly Speck (on apples).
Cyprex 65-W and Cyprex 3% and 4% dusts have given outstanding control
of pear scab. Cyprex 65-W has given outstanding control of leaf spot
in all regions of North America where the disease is economically
important (on cherries) (30d).
II. PHYSICAL PROPERTIES
MOLECULAR FORMULA: C15 H33 N3 O2 (26)
MOLECULAR WEIGHT: 287.4 (26)
PHYSICAL STATE: Colorless crystals (pure compound) (26)
MELTING POINT: 136 C (pure compound) (26)
SOLUBILITY: Soluble in water (pure compound) (26)
III. HEALTH HAZARD INFORMATION
OSHA STANDARD: NA
NIOSH RECOMMENDED LIMIT: NA
ACGIH RECOMMENDED LIMIT: NA
A. ACUTE TOXICITY
DERMAL: LD50 = >1500 mg/kg (rabbit, by single 24-hour skin
ORAL: LD50 = about 1000 mg/kg (male rat) (56).
EYES: Concentrated material causes eye irritation (30d).
B. SUBACUTE AND CHRONIC TOXICITY:
In 2-year feeding trials rats receiving 800 mg/kg diet suffered a
slight retardation of growth with no effect on reproduction or
IV. ENVIRONMENTAL CONSIDERATIONS
Nonhazardous to bees. Phytotoxic effects on some varieties of
apples, peaches, plums and nuts (48).
V. EMERGENCY AND FIRST AID PROCEDURES
The chemical information provided below has been condensed
from original source documents, primarily from "Recognition and
Management of Pesticide Poisonings", 3rd ed. by Donald P. Morgan,
which have been footnoted. This information has been provided in
this form for your convenience and general guidance only. In
specific cases, further consultation and reference may be required
and is recommended. This information is not intended as a sub-
stitute for a more exhaustive review of the literature nor for the
judgement of a physician or other trained professional.
If poisoning is suspected, do not wait for symptoms to develop.
Contact a physician, the nearest hospital, or the nearest Poison
EYE CONTACT: Flush with plenty of water for at least fifteen
minutes and get medical attention (30d).
VI. FIRE AND EXPLOSION INFORMATION
To be developed.
Incompatible with chlorobenzilate, lime, oils and oil emulsions.
Hard water causes some incompatibility (48).
VIII. PROTECTIVE MEASURES
STORAGE AND HANDLING: Do not get in eyes or on skin. Do not breathe
dust. Keep container closed when not in use. Transfer or mix product
under conditions of adequate ventilation. Do not contaminate food or
feed products. Store this product away from food or feed. The
biological activity of the product remains practically unvaried for 3
years under environmental conditions, provided the product is stored in
its unopened and undamaged original containers, in shaded and possibly
well-aired places (56).
PROTECTIVE CLOTHING: Wear goggles or face shield when handling. Wear
rubber gloves when handling and wash thoroughly after work (56).
IX. PROCEDURES FOR SPILLS AND LEAKS
IN CASE OF EMERGENCY, CALL, DAY OR NIGHT
PESTICIDE TEAM SAFETY NETWORK/CHEMTREC
X. LITERATURE CITED
26. The Pesticide Manual: A World Compendium, 6th ed. 1979. C. R.
Worthing, ed. The British Crop Protection Council, Croydon,
England. 655 pp.
30d. American Cyanamid Company, Agricultural Division. 1966. Technical
information: Cyprex fruit fungicide. Princeton, NJ.
48. Harding, W.C. 1979-80. Pesticide profiles, part two: fungicides
and nematicides. Univ. Maryland, Coop. Ext. Service Bull.
283, 22 pp.
56. Farm Chemicals Handbook, 70th ed. 1984. R. T. Meister, G. L.
Berg, C. Sine, S. Meister, and J. Poplyk, eds. Meister
Publishing Co., Willoughby, OH.