triflumizole (Terraguard, Procure) Registration 8/95
August 3, 1995
Ms. Judith Ball
Uniroyal Chemical Company, Inc.
74 Amity Road
Bethany, CT 06524-3402
Dear Ms. Ball:
Re: Registration of Terraguard 50W (EPA Reg. No. 400-433) containing
the New Active Ingredient Triflumizole
The New York State Department of Environmental Conservation has accepted
your application to register the pesticide product Terraguard 50W
Fungicide for use as a protectant soak, soil drench, foliar spray or
through chemigation for control of certain diseases on ornamentals grown
in enclosed commercial structures such as greenhouses, shadehouses,
nurseries, and interiorscapes.
Terraguard 50W contains 50% of the new active ingredient Triflumizole
(chemical name: 1-[1-[[4-chloro-2-(trifluoromethyl)phenyl]imino]-2-
propoxyethyl]-H-imidazole). It may be applied weekly or biweekly as
needed, at a single rate of 16 oz/100 gallons of water, or 1 lb active
ingredient/acre with 12 to 24 applications per year.
The data package was submitted for review to the Division of Water
(DOW), the Division of Fish and Wildlife (DF&W), and the New York State
Department of Health (NYSDOH).
The Bureau of Environmental Protection, DF&W has reviewed the data
package and determined that the labelled indoor uses of Terraguard 50W
should not adversely impact the fish and wildlife resources of New York
The DOW, in its review, has concluded that labelled use of Terraguard
50W in New York State is unlikely to result in significant impacts to
groundwater resources. The active ingredient degrades rapidly relative
to other compounds and does not appear to have a high propensity to
The NYSDOH has stated in their review that in acute animal studies
triflumazole was not very toxic by the oral, dermal and inhalation
routes. However, triflumazole caused severe eye irritation in rabbits
and mild dermal sensitization in guinea pigs. Triflumazole does not
appear to have oncogenic potential, is not very persistent, and does not
bioaccumulate greatly. While some reproductive effects were noted, the
annual average daily exposure for workers is expected to be more than
900 times lower than the RfD for triflumazole.
The proposed label for Terraguard 50W requires that applictors and other
handlers wear protective clothing (including eyewear) and risks to
workers are expected to be low. Therefore, DOH does not object to the
registration of Terraguard 50W in New York State
Enclosed are your certificate of registration and stamped accepted label
for your files.
If you have any questions on this matter, please contact Maureen
Serafini, Supervisor of our Pesticide Product Registration Section, at
Norman H. Nosenchuck, P.E.
Division of Hazardous Substances Regulation