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triforine (Funginex) Chemical Profile 2/85

                                     triforine

      CHEMICAL NAME:      N,N'-[1,4-Piperazinediyl-bis(2,2,2-trichloroethyl-
                          idene)]-bis-[formamide] (56)

      TRADE NAME(S):      Funginex, Saprol (56)

      FORMULATION(S):     Emulsifiable concentrate, 18.2% triforine; 6.5%
                          EC; wettable powder, 50% (56).

      TYPE:               Piperazine-derived fungicide

      BASIC PRODUCER(S):  Celemerck GmbH and Co. KG
                          P.O. Box 202
                          6507 Ingelheim/Rhein
                          West Germany
                          06132-771

      STATUS:             General use

      PRINCIPAL USES:  For use against powdery mildew, scab, rust, and
      other diseases of fruits, vegetables, cereals, and ornamentals.
      Registered for the control of scab, powdery mildew, and rust on
      apples; brown rot blossom rot on peaches, nectarines, apricots;
      mummyberry disease on high bush blueberries; powdery mildew, black
      spot, and rust on roses; powdery mildew, rust on various other
      ornamentals.  For postharvest control of brown rot on peaches,
      nectarines, apricots, cherries, plums (56).


                                  I.  EFFICACY

           To be developed.


                             II.  PHYSICAL PROPERTIES

      MOLECULAR FORMULA:  C10 H14 Cl6 N4 O2 (26)

      MOLECULAR WEIGHT:   435.0 (26)

      PHYSICAL STATE:     Colorless crystals (pure compound) (26)

      MELTING POINT:      155 C (pure compound) (26)

      VAPOR PRESSURE:     2 x 10-7 mmHg at 25 C (pure compound) (26)

      SOLUBILITY:         27-20 mg/l water at room temperature (pure
                          compound) (26)


                          III.  HEALTH HAZARD INFORMATION

      OSHA STANDARD:  NA

      NIOSH RECOMMENDED LIMIT:  NA

      ACGIH RECOMMENDED LIMIT:  NA

      TOXICOLOGY

           A.  ACUTE TOXICITY

               DERMAL:  LD50 = >10,000 mg/kg (technical, rabbit) (56)

               ORAL:    LD50 = >16,000 mg/kg (technical, male and female
                        rats) (56)

           B.  SUBACUTE AND CHRONIC TOXICITY:

           To be developed.


                        IV.  ENVIRONMENTAL  CONSIDERATIONS

           Little or no hazard to fish and honey bees.  Phytotoxic to certain
      pear varieties (48).
           Nonpersistent in the soil.  Half-life in soil is approximately 3
      weeks (48).
           The acute oral LD50 for quail is >6000 mg/kg.  It is nontoxic to
      guppies at 50 mg/l; nontoxic to honey bees (26).


                      V.  EMERGENCY AND FIRST AID PROCEDURES

           The chemical information provided below has been condensed
      from original source documents, primarily from "Recognition and
      Management of Pesticide Poisonings", 3rd ed. by Donald P.  Morgan,
      which have been footnoted.  This information has been provided in
      this form for your convenience and general guidance only.  In
      specific cases, further consultation and reference may be required
      and is recommended.  This information is not intended as a sub-
      stitute for a more exhaustive review of the literature nor for the
      judgement of a physician or other trained professional.

           If poisoning is suspected, do not wait for symptoms to develop.
      Contact a physician, the nearest hospital, or the nearest Poison
      Control Center.

           To be developed.


                        VI.  FIRE AND EXPLOSION INFORMATION

           To be developed.


                                VII.  COMPATIBILITY

           Compatible with most other pesticides.  Do not mix with wetting
      agents, spreader-stickers or other adjuvants (48).


                            VIII.  PROTECTIVE MEASURES

      STORAGE AND HANDLING:  Store in a cool, dry place; avoid prolonged
      exposure above 100 F (56).

      PROTECTIVE CLOTHING:  Wear goggles or face shield and rubber gloves
      when handling (56).


                       IX.  PROCEDURES FOR SPILLS AND LEAKS

                     IN CASE OF EMERGENCY, CALL, DAY OR NIGHT
                                  (800) 424-9300
                      PESTICIDE TEAM SAFETY NETWORK/CHEMTREC


                               X.  LITERATURE CITED

      26.  The Pesticide Manual:  A World Compendium, 6th ed.  1979.  C. R.
               Worthing, ed.  The British Crop Protection Council, Croydon,
               England.  655 pp.

      48.  Harding, W.C.  1979-80.  Pesticide profiles, part two:  fungicides
               and nematicides.  Univ. Maryland, Coop. Ext. Service Bull.
               283, 22 pp.

      56.  Farm Chemicals Handbook, 70th ed.  1984.  R. T. Meister, G. L.
               Berg, C. Sine, S. Meister, and J. Poplyk, eds.  Meister
               Publishing Co., Willoughby, OH.

      2/5/85