zineb (Dithane Z-78, Parzate) Chemical Profile 2/85
CHEMICAL NAME: Zinc ethylenebisdithiocarbamate (56)
TRADE NAME(S): Dithane Z-78, Parzate, Polyram Z (56)
FORMULATION(S): Wettable powder 80%, dust 10%, WP 70% (56).
Frequently tank-mixed or combined with other
TYPE: Carbamate fungicide
BASIC PRODUCER(S): FMC Corp., Agricultural Chemical Group
2000 Market St.
Philadelphia, PA 19103
Rohm and Haas Co.
Independence Mall West
Philadelphia, PA 19105
STATUS: General use
PRINCIPAL USES: Foliar protectant against a variety of diseases on
fruits, vegetables, and ornamentals. Also used as seed and soil
Used to protect foliage and fruit of a wide range of crops against
diseases such as potato and tomato blight, Botrytis spp., downy mildews
and rusts (26).
Used especially on citrus for control of greasy spot and to extend
control of citrus rust mite. Zineb also results from combining nabam
(or diammonium or potassium ammonium analogs) with zinc sulfate in the
spray tank (56).
To be developed.
II. PHYSICAL PROPERTIES
MOLECULAR FORMULA: (C4 H6 N2 S4 Zn)x (26)
MOLECULAR WEIGHT: (275.8)x (26)
PHYSICAL STATE: Light-colored powder (pure compound) (26)
MELTING POINT: Decomposes without melting (pure compound) (26)
VAPOR PRESSURE: Negligible at room temperature (pure compound) (26)
SOLUBILITY: At room temperature c. 10 mg/l water (pure compound)
III. HEALTH HAZARD INFORMATION
OSHA STANDARD: NA
NIOSH RECOMMENDED LIMIT: NA
ACGIH RECOMMENDED LIMIT: NA
A. ACUTE TOXICITY
ORAL: LD50 = >5200 mg/kg (rat) (26)
B. SUBACUTE AND CHRONIC TOXICITY:
To be developed.
IV. ENVIRONMENTAL CONSIDERATIONS
Nonhazardous to honey bees. Phytotoxic to zinc-sensitive plants
such as tobacco and cucurbits (48).
V. EMERGENCY AND FIRST AID PROCEDURES
The chemical information provided below has been condensed
from original source documents, primarily from "Recognition and
Management of Pesticide Poisonings", 3rd ed. by Donald P. Morgan,
which have been footnoted. This information has been provided in
this form for your convenience and general guidance only. In
specific cases, further consultation and reference may be required
and is recommended. This information is not intended as a sub-
stitute for a more exhaustive review of the literature nor for the
judgement of a physician or other trained professional.
If poisoning is suspected, do not wait for symptoms to develop.
Contact a physician, the nearest hospital, or the nearest Poison
SYMPTOMS AND SIGNS OF POISONING
Ethylene bis dithiocarbamates and (mono) thiocarbamates - Some of
these agents are irritating to skin and respiratory mucous membranes,
causing ITCHING, SCRATCHY THROAT, SNEEZING, and COUGH, if excessive
amounts of spray or dust are inhaled. Apart from this effect, toxic
potential is low. Neurotoxic and post-ethanol "Antabuse" reactions are
not known to occur as a result of contact with these particular
SKIN CONTACT: Wash contaminating chemical from skin and hair with
soap and water (25).
INGESTION: Give Syrup of Ipecac, followed by 1-2 glasses of
water, to induce vomiting (adults: 30 ml; children under 12 years: 15
INHALATION: Remove subject to fresh air (16).
EYE CONTACT: Flush contaminant from eyes with fresh water for
10-15 minutes (25).
NOTES TO PHYSICIAN:
If an ETHYLENE BIS DITHIOCARBAMATE, or (mono) thiocarbamate have
A. Give SYRUP OF IPECAC, followed by 1-2 glasses of water, to induce
vomiting (adults: 30 ml; children under 12 years: 15 ml).
Following emesis, administer 30-50 gm ACTIVATED CHARCOAL to bind
toxicant remaining in the gut.
B. Follow charcoal with SODIUM or MAGNESIUM SULFATE, 0.25 gm/kg, to
remove toxicant from the gut by catharsis (25).
VI. FIRE AND EXPLOSION INFORMATION
GENERAL: Flash point: 200 C OC.
Special fire fighting procedures: wear self-contained breathing
equipment. Use water spray to cool fire exposed containers.
Unusual fire and explosion hazards: Toxic and flammable gases are
evolved when material is heated above 176 F (80 C) (16).
EXTINGUISHER TYPE: CO2, dry chemical, water fog (16).
Compatible with other fungicides and insecticides except alkaline
or mercury compounds (48).
VIII. PROTECTIVE MEASURES
STORAGE AND HANDLING: Store in a cool, dry place. Do not
contaminate food, feed, domestic water supplies, streams, ponds or
other water. Keep out of reach of children. Use only in accordance
with label. Do not reuse container (16).
PROTECTIVE CLOTHING: Impervious gloves, safety glasses; wear
washable work clothes to be washed before reuse (16).
PROTECTIVE EQUIPMENT: If needed, use Wilson Agritox #2 respirator
with R21 cartridge and R15 filter (16).
IX. PROCEDURES FOR SPILLS AND LEAKS
IN CASE OF EMERGENCY, CALL, DAY OR NIGHT
PESTICIDE TEAM SAFETY NETWORK/CHEMTREC
Using approved respirator, carefully sweep up material and use as
per label on package for disposal. Wash area with soap and water. Dry
with kitty litter or sawdust. Unusable material must go to an approved
chemical disposal site (16).
X. LITERATURE CITED
16. Agway, Inc., Chemical Division. Material safety data sheet.
25. Morgan, D.P. 1982. Recognition and management of
pesticide poisonings, 3rd ed. U. S. Environmental Protection
Agency, Washington, DC. 120 pp.
26. The Pesticide Manual: A World Compendium, 6th ed. 1979. C. R.
Worthing, ed. The British Crop Protection Council, Croydon,
England. 655 pp.
48. Harding, W.C. 1979-80. Pesticide profiles, part two: fungicides
and nematicides. Univ. Maryland, Coop. Ext. Service Bull.
283, 22 pp.
56. Farm Chemicals Handbook, 70th ed. 1984. R. T. Meister, G. L.
Berg, C. Sine, S. Meister, and J. Poplyk, eds. Meister
Publishing Co., Willoughby, OH.