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allidochlor (Randox) Herbicide Profile 3/85

                                 allidochlor (CDAA)
      CHEMICAL NAME:      N-N-diallyl-2-chloroacetamide (58)
      TRADE NAME(S):      Randox (56)
      FORMULATION(S):     Emulsifiable concentrate (4 lb/gal); granule (20%)
                          (58).
      TYPE:               Acetamide herbicide
      BASIC PRODUCER(S):  Monsanto Agricultural Products Co.
                          800 N. Lindbergh Blvd.
                          St. Louis, MO 63167
      PRINCIPAL USES:  For control of most annual grasses and certain
      broadleaf weeds.  Tolerant crops are corn (all types), sorghum (all
      types), soybeans, lima, snap and dry beans, cabbage, canning peas,
      onions, celery and certain fruits and ornamentals (58).
      APPLICATION METHODS:  Preemergence (surface applied) and postemergence
      (58).
                                   I.  EFFICACY
           Important weeds controlled:  Annual bluegrass, barnyardgrass,
      cheat, carpetweed, crabgrass, foxtail, purslane, pigweed, and many
      others.
           Excessive rainfall (3 inches or more) following the treatment may
      dilute the chemicals giving poor weed control.  When treating wet soil
      the chemical may be lost in the air very rapidly.  Perennial or
      established weeds are not controlled.  Effective on peat, muck, or high
      clay soils.  Moisture is required to activate (8b).
      Randox controls these weeds:
      annual bluegrass               Poa annua
      barnyardgrass (watergrass)     Echinochloa crusgalli
      carelessweed                   Amaranthus palmeri
      carpetweed                     Mollugo verticillata
      cheat                          Bromus secalinus
      crabgrass                      Digitaria spp.
      giant foxtail (wild millet)    Setaria faberii
      green foxtail                  Setaria viridis
      yellow foxtail                 Setaria glauca
      pigweed (redroot)              Amaranthus retroflexus
      pigweed (spiny)                Amaranthus spinosus
      purslane                       Portulaca oleracea
      stinkgrass                     Eragrostis cilianensis
      Weeds not controlled:
      grass perennials
      bermudagrass                   Cynodon dactaylon
      johnsongrass                   Sorghum halepense
      nutgrass                       Cyperus spp.
      quackgrass                     Agropyron repens
      broadleaf perennials
      cocklebur                      Xanthrum spp.
      field bindweed                 Convolvulus arvensis (55c).
                             II.  PHYSICAL PROPERTIES
      MOLECULAR FORMULA:  C8 H12 C1 N0 (58)
      MOLECULAR WEIGHT:   173.6 (58)
      PHYSICAL STATE:     Oily, amber liquid (pure compound) (58)
      ODOR:               Slightly irritating odor (pure compound) (58)
      MELTING POINT:      Liquid at room temperature (pure compound) (58)
      BOILING POINT:      74 C at 0.3 mmHg (pure compound) (58)
      VAPOR PRESSURE:     9.4 x 10-3 mmHg at 20 C (pure compound) (58)
      SOLUBILITY:         20 g/kg water (2%) at 25 C (pure compound) (58)
                          III.  HEALTH HAZARD INFORMATION
      OSHA STANDARD:  NA
      NIOSH RECOMMENDED LIMIT:  NA
      ACGIH RECOMMENDED LIMIT:  NA
      TOXICOLOGY
           A.  ACUTE TOXICITY
               DERMAL:    a.  technical product
                                Rabbit dermal LD50 - 830 mg/kg
                                Rabbit skin irritation - corrosive
                                On the basis of human exposure to CDAA, it is
                                concluded that this material can produce skin
                                sensitization in susceptible individuals (58).
                          b.  Randox EC
                                Rabbit dermal LD50 - 590 mg/kg
                                Rabbit skin irritation - corrosive
                                On the basis of human exposure to Randox
                                formulations, it is concluded that Randox EC
                                may produce skin sensitization in susceptible
                                individuals.  However, based on reported
                                cases of skin sensitization, it appears that
                                the incidence of allergic skin reaction is
                                low (58).
                          c.  Randox Granular
                                Rabbit dermal LD50 - 4750 mg/kg
                                Rabbit skin irritation - Primary irritation
                                index 6.1 on a scale of 8.0.  Severely
                                irritating (58).
                 ORAL:    LD50 = 290 mg/kg (technical product); 210 mg/kg
                            (rat, Randox EC); 1900 mg/kg (rat, Randox Granular)
                            (58).
                          LD50 = 700 mg/kg (rat) (62)
                 EYES:    a.  technical product
                              Rabbit eye irritation - corrosive (58).
                          b.  Randox EC
                              Rabbit eye irritation - average score on a scale
                              of 110.0 of 24-, 48-, and 72-hour readings was
                              48.0.  This material is considered to be severely
                              irritating to rabbit eyes (58).
                          c.  Randox Granular
                              Rabbit eye irritation - Average score on a scale
                              of 110.0 of 240, 48-, and 72-hour readings was
                              25.0.  Moderately irritating (58).
           B.  SUBACUTE AND CHRONIC TOXICITY:
           No deleterious effects were observed in rats and dogs fed diets
      containing up to 200 ppm (highest dietary level tested) CDAA for 90
      days (58).
                        IV.  ENVIRONMENTAL  CONSIDERATIONS
      Behavior In Or On Soils
      1.  Adsorption and leaching characteristics in basic soil types:
            Adsorption directly proportional to colloidal content of soil.
      2.  Microbial breakdown:  Main route of degradation.
      3.  Loss from photodecomposition and/or volatilization:  CDAA is
            slightly volatile from moist soil and volatilization is retarded
            with soil incorporation.
      4.  Resultant average persistence at recommended rates:  Three to 6
            weeks, with shorter persistence on soils of low colloid content
            (58).
      General toxicity to wildlife and fish:
      1.  Wildlife - technical
            Eight-day dietary LC50 in bobwhite quail - greater than 10,000
            ppm.
            Eight-day dietary LC50 in mallard ducks - greater than 10,000
            ppm.
      2.  Wildlife - Randox EC
            Eight-day dietary LC50 in bobwhite quail - greater than 5020 ppm.
      3.  Aquatic organisms - Randox EC
            96-hour LC50 rainbow trout 2.0 ppm.
            96-hour LC50 in bluegill sunfish - 6.6 ppm (58).
                      V.  EMERGENCY AND FIRST AID PROCEDURES
           The chemical information provided below has been condensed
      from original source documents, primarily from "Recognition and
      Management of Pesticide Poisonings", 3rd ed. by Donald P.  Morgan,
      which have been footnoted.  This information has been provided in
      this form for your convenience and general guidance only.  In
      specific cases, further consultation and reference may be required
      and is recommended.  This information is not intended as a sub-
      stitute for a more exhaustive review of the literature nor for the
      judgement of a physician or other trained professional.
           If poisoning is suspected, do not wait for symptoms to develop.
      Contact a physician, the nearest hospital, or the nearest Poison
      Control Center.
      KNOWN OR SUSPECTED ADVERSE EFFECTS:  Moderately irritating to
      skin and eyes (25).
      Outward toxicity symptoms in rats showed excessive salivation,
      discomfort, coma, and convulsions.  Diarrhea occurred in animals
      surviving 12 to 36 hours.  Liver degeneration occurred (58).
           SKIN CONTACT:  Wash contaminated skin with soap and water (25).
           INGESTION:  Induce vomiting if swallowed (58).
           EYE CONTACT:  Flush contaminated eyes with copious amounts of
      fresh water for 15 minutes (25).
                        VI.  FIRE AND EXPLOSION INFORMATION
           Nonflammable.  Closed cup analytical CDAA 124 C; closed cup
      technical CDAA  54 C (58).
                                VII.  COMPATIBILITY
           No incompatibilities known at present.  Noncorrosive to No. 316 and
      304 stainless steel, aluminum and heresite.  Corrosive to ordinary steel
      (58).
                            VIII.  PROTECTIVE MEASURES
      STORAGE AND HANDLING:  Indefinitely stable.  Not sensitive to light or
      heat.  Handle only with adequate ventilation.  Wear rubber gloves and
      goggles.  Avoid contact with eyes, skin, and clothing.  Contaminated
      clothing must be laundered before reuse (58).
                       IX.  PROCEDURES FOR SPILLS AND LEAKS
                     IN CASE OF EMERGENCY, CALL, DAY OR NIGHT
                                  (800) 424-9300
                      PESTICIDE TEAM SAFETY NETWORK/CHEMTREC
                               X.  LITERATURE CITED
       8b. Thomson, W.T.  1981.  Agricultural chemicals - book 2:
               herbicides.  Revised ed.  Thomson Publications, Fresno, CA.
               274 pp.
      25.  Morgan, D.P.  1982.  Recognition and management of pesticide
               poisonings, 3rd ed.  U.S. Environmental Protection Agency,
               Washington, DC.  120 pp.
      55c. Monsanto Company, Agricultural Division.  1975.  Specimen label:
               Randox herbicide.  St. Louis, MO.
      56.  Farm Chemicals Handbook, 70th ed.  1984.  R. T. Meister, G. L.
               Berg, C. Sine, S. Meister, and J. Poplyk, eds.  Meister
               Publishing Co., Willoughby, OH.
      58.  Weed Science Society of America, Herbicide Handbook Committee.
               1983.  Herbicide handbook of the weed science society of
               America, 5th ed.  Weed Science Society of America, Champaign,
               IL.  515 pp.
      62.  The Pesticide Manual:  A World Compendium, 7th ed.  1983.  C.R.
               Worthing, ed.  The British Crop Protection Council, Croydon,
               England.  695 pp.
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