allidochlor (Randox) Herbicide Profile 3/85
CHEMICAL NAME: N-N-diallyl-2-chloroacetamide (58)
TRADE NAME(S): Randox (56)
FORMULATION(S): Emulsifiable concentrate (4 lb/gal); granule (20%)
TYPE: Acetamide herbicide
BASIC PRODUCER(S): Monsanto Agricultural Products Co.
800 N. Lindbergh Blvd.
St. Louis, MO 63167
PRINCIPAL USES: For control of most annual grasses and certain
broadleaf weeds. Tolerant crops are corn (all types), sorghum (all
types), soybeans, lima, snap and dry beans, cabbage, canning peas,
onions, celery and certain fruits and ornamentals (58).
APPLICATION METHODS: Preemergence (surface applied) and postemergence
Important weeds controlled: Annual bluegrass, barnyardgrass,
cheat, carpetweed, crabgrass, foxtail, purslane, pigweed, and many
Excessive rainfall (3 inches or more) following the treatment may
dilute the chemicals giving poor weed control. When treating wet soil
the chemical may be lost in the air very rapidly. Perennial or
established weeds are not controlled. Effective on peat, muck, or high
clay soils. Moisture is required to activate (8b).
Randox controls these weeds:
annual bluegrass Poa annua
barnyardgrass (watergrass) Echinochloa crusgalli
carelessweed Amaranthus palmeri
carpetweed Mollugo verticillata
cheat Bromus secalinus
crabgrass Digitaria spp.
giant foxtail (wild millet) Setaria faberii
green foxtail Setaria viridis
yellow foxtail Setaria glauca
pigweed (redroot) Amaranthus retroflexus
pigweed (spiny) Amaranthus spinosus
purslane Portulaca oleracea
stinkgrass Eragrostis cilianensis
Weeds not controlled:
bermudagrass Cynodon dactaylon
johnsongrass Sorghum halepense
nutgrass Cyperus spp.
quackgrass Agropyron repens
cocklebur Xanthrum spp.
field bindweed Convolvulus arvensis (55c).
II. PHYSICAL PROPERTIES
MOLECULAR FORMULA: C8 H12 C1 N0 (58)
MOLECULAR WEIGHT: 173.6 (58)
PHYSICAL STATE: Oily, amber liquid (pure compound) (58)
ODOR: Slightly irritating odor (pure compound) (58)
MELTING POINT: Liquid at room temperature (pure compound) (58)
BOILING POINT: 74 C at 0.3 mmHg (pure compound) (58)
VAPOR PRESSURE: 9.4 x 10-3 mmHg at 20 C (pure compound) (58)
SOLUBILITY: 20 g/kg water (2%) at 25 C (pure compound) (58)
III. HEALTH HAZARD INFORMATION
OSHA STANDARD: NA
NIOSH RECOMMENDED LIMIT: NA
ACGIH RECOMMENDED LIMIT: NA
A. ACUTE TOXICITY
DERMAL: a. technical product
Rabbit dermal LD50 - 830 mg/kg
Rabbit skin irritation - corrosive
On the basis of human exposure to CDAA, it is
concluded that this material can produce skin
sensitization in susceptible individuals (58).
b. Randox EC
Rabbit dermal LD50 - 590 mg/kg
Rabbit skin irritation - corrosive
On the basis of human exposure to Randox
formulations, it is concluded that Randox EC
may produce skin sensitization in susceptible
individuals. However, based on reported
cases of skin sensitization, it appears that
the incidence of allergic skin reaction is
c. Randox Granular
Rabbit dermal LD50 - 4750 mg/kg
Rabbit skin irritation - Primary irritation
index 6.1 on a scale of 8.0. Severely
ORAL: LD50 = 290 mg/kg (technical product); 210 mg/kg
(rat, Randox EC); 1900 mg/kg (rat, Randox Granular)
LD50 = 700 mg/kg (rat) (62)
EYES: a. technical product
Rabbit eye irritation - corrosive (58).
b. Randox EC
Rabbit eye irritation - average score on a scale
of 110.0 of 24-, 48-, and 72-hour readings was
48.0. This material is considered to be severely
irritating to rabbit eyes (58).
c. Randox Granular
Rabbit eye irritation - Average score on a scale
of 110.0 of 240, 48-, and 72-hour readings was
25.0. Moderately irritating (58).
B. SUBACUTE AND CHRONIC TOXICITY:
No deleterious effects were observed in rats and dogs fed diets
containing up to 200 ppm (highest dietary level tested) CDAA for 90
IV. ENVIRONMENTAL CONSIDERATIONS
Behavior In Or On Soils
1. Adsorption and leaching characteristics in basic soil types:
Adsorption directly proportional to colloidal content of soil.
2. Microbial breakdown: Main route of degradation.
3. Loss from photodecomposition and/or volatilization: CDAA is
slightly volatile from moist soil and volatilization is retarded
with soil incorporation.
4. Resultant average persistence at recommended rates: Three to 6
weeks, with shorter persistence on soils of low colloid content
General toxicity to wildlife and fish:
1. Wildlife - technical
Eight-day dietary LC50 in bobwhite quail - greater than 10,000
Eight-day dietary LC50 in mallard ducks - greater than 10,000
2. Wildlife - Randox EC
Eight-day dietary LC50 in bobwhite quail - greater than 5020 ppm.
3. Aquatic organisms - Randox EC
96-hour LC50 rainbow trout 2.0 ppm.
96-hour LC50 in bluegill sunfish - 6.6 ppm (58).
V. EMERGENCY AND FIRST AID PROCEDURES
The chemical information provided below has been condensed
from original source documents, primarily from "Recognition and
Management of Pesticide Poisonings", 3rd ed. by Donald P. Morgan,
which have been footnoted. This information has been provided in
this form for your convenience and general guidance only. In
specific cases, further consultation and reference may be required
and is recommended. This information is not intended as a sub-
stitute for a more exhaustive review of the literature nor for the
judgement of a physician or other trained professional.
If poisoning is suspected, do not wait for symptoms to develop.
Contact a physician, the nearest hospital, or the nearest Poison
KNOWN OR SUSPECTED ADVERSE EFFECTS: Moderately irritating to
skin and eyes (25).
Outward toxicity symptoms in rats showed excessive salivation,
discomfort, coma, and convulsions. Diarrhea occurred in animals
surviving 12 to 36 hours. Liver degeneration occurred (58).
SKIN CONTACT: Wash contaminated skin with soap and water (25).
INGESTION: Induce vomiting if swallowed (58).
EYE CONTACT: Flush contaminated eyes with copious amounts of
fresh water for 15 minutes (25).
VI. FIRE AND EXPLOSION INFORMATION
Nonflammable. Closed cup analytical CDAA 124 C; closed cup
technical CDAA 54 C (58).
No incompatibilities known at present. Noncorrosive to No. 316 and
304 stainless steel, aluminum and heresite. Corrosive to ordinary steel
VIII. PROTECTIVE MEASURES
STORAGE AND HANDLING: Indefinitely stable. Not sensitive to light or
heat. Handle only with adequate ventilation. Wear rubber gloves and
goggles. Avoid contact with eyes, skin, and clothing. Contaminated
clothing must be laundered before reuse (58).
IX. PROCEDURES FOR SPILLS AND LEAKS
IN CASE OF EMERGENCY, CALL, DAY OR NIGHT
PESTICIDE TEAM SAFETY NETWORK/CHEMTREC
X. LITERATURE CITED
8b. Thomson, W.T. 1981. Agricultural chemicals - book 2:
herbicides. Revised ed. Thomson Publications, Fresno, CA.
25. Morgan, D.P. 1982. Recognition and management of pesticide
poisonings, 3rd ed. U.S. Environmental Protection Agency,
Washington, DC. 120 pp.
55c. Monsanto Company, Agricultural Division. 1975. Specimen label:
Randox herbicide. St. Louis, MO.
56. Farm Chemicals Handbook, 70th ed. 1984. R. T. Meister, G. L.
Berg, C. Sine, S. Meister, and J. Poplyk, eds. Meister
Publishing Co., Willoughby, OH.
58. Weed Science Society of America, Herbicide Handbook Committee.
1983. Herbicide handbook of the weed science society of
America, 5th ed. Weed Science Society of America, Champaign,
IL. 515 pp.
62. The Pesticide Manual: A World Compendium, 7th ed. 1983. C.R.
Worthing, ed. The British Crop Protection Council, Croydon,
England. 695 pp.