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brominated salicylanide (Temasept IV) Chemical Fact Sheet 9/85

CHEMICAL FACT SHEET FOR:  BROMINATED SALICYLANIDE

FACT SHEET NUMBER:  67

DATE ISSUED:  SEPTEMBER 30, 1985

                1. DESCRIPTION OF CHEMICAL

- Generic Name:  3,4',5 Tribromosalicylanilide
- Common Name:  tribromsalan, TBS
- Trade Name:  Temasept IV
- EPA Shaughnessy Code:  077404
- Chemical Abstracts Service (CAS) No.:  87-10-5

- Generic Name:  3,5 dibromosalicylanilide
- Common Name:  N/A
- Trade Name:  N/A
- EPA Shaughnessy Code:  077405
- Chemical Abstracts Service (CAS) No.:  2577-72-2

- Generic Name:  4',5 dibromosalicylanilide
- Common Name:  N/A
- Trade Name:  N/A
- EPA Shaughnessy Code:  077402
- Chemical Abstracts Service (CAS) No.:  87-12-7
- Year of Initial Registration:  1964

- Pesticide Type:  antimicrobial, preservative
- Chemical Family:  brominated salicylanilides
- U.S. Producers:  Hexcel Corporation, Sherwin Williams Chemicals

                 2. USE PATTERNS AND FORMULATIONS

- Application sites:  Hard surfaces, laundry, textiles, and manufactured
  products. 
- Types of formulations:  Solid, solutions, and sprays 
- Application rates:  N/A 
- Usual carriers:  Soap

                   3. SCIENCE FINDINGS

Chemical Characteristics:

- Physical state:  Powder 
- Color:  White 
- Odor:  None 
- Melting point:  227-228 degrees 
- Density:  No data available 
- Solubility:  Soluble (0.5-4.0%) in methanol, ethanol, isopropanol,
  ethyl ether, and benzene; sparingly soluble (0.01-0.5%) in chloroform
  and cyclohexane; insoluble in water and petroleum ether.

Toxicological Characteristics:

     There are no available data to assess the potential toxicity of the 
brominated salicylanilides.

- Physiological and Biochemical Behavioral Characteristics:  N/A

Environmental Characteristics:

     Indoor uses only. Limited exposure 15 possible based on the 
registered uses of these products as disinfectants, laundry additives, 
textile preservatives, and manufactured products.

Ecological Characteristics:

     Indoor uses only. Limited exposure is possible based on the 
registered uses of these products as disinfectants, laundry additives, 
textile preservatives, and manufactured products.

Tolerance Assessment:

     N/A. The registered uses of the brominated salicylanilides do not 
include direct application to a food or feed crop.

Problems Known to Have Occurred With Use of the Chemical:  None.

         4. SUMMARY OF REGULATORY POSITION AND RATIONALE

     No data are available to establish whether or not the risk criteria 
listed in Section 162.11(a) of Title 40 of the U.S. Code of Federal 
Regulations have been met or exceeded.

- Unique warning statements: None

                   5. SUMMARY OF MAJOR DATA GAPS

     Toxicology, environmental fate, fish and wildlife, and product 
chemistry data are required to assess the hazard associated with the 
registered uses of these chemicals.

- Efficacy data:  Product-specific microbiological efficacy data will be 
required for all health related uses.

                      6. CONTACT PERSON AT EPA

A. E. Castillo
Product Manager 32
Disinfectants Branch
Registration Division (TS-767C)
401 M Street S.W.
Washington, DC 20460
703/557-3964

DISCLAIMER:  THE INFORMATION PRESENTED IN THIS CHEMICAL 
INFORMATION FACT SHEET IS FOR INFORMATIONAL PURPOSES ONLY AND NOT TO BE
USED TO FULFILL DATA REOUIREMENTS FOR PESTICIDE REGISTRATION AND 
REREGISTRATION.